Repairing Damage After Injury
suggests that creatine supplements may help prevent muscle damage and enhance the recovery process after an athlete has experienced an injury.
Creatine may also have an antioxidant effect after an intense session of resistance training, and it may help reduce cramping. It may have a role in rehabilitation for brain and other injuries.
Blood And Urinary Analyses
Blood samples were obtained from an antecubital vein, following a 12-h overnight fasting. Participants followed their normal diet consumption during the 24-h urine collection. Urine samples were stored at approximately 4Â°C. Both blood and urinary measurements were performed in the morning. Creatinine was determined using Jaffes kinetic method. Urinary and serum sodium and potassium were assessed by using a flame photometer . Urea was assessed by an UV-kinetic method. Albuminuria was determined by nephelometry and proteinuria was measured through the benzethonium chloride method.
All of the samples were analyzed in duplicate and the CV were 2.0, 2.2, 1.1, 2.1, 2.3, 5.3, 24.5, and 16.4% for serum creatinine, serum sodium, serum potassium, serum urea, proteinuria, albuminuria, urinary sodium, and urinary potassium, respectively.
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What Are Vitamins And Minerals
Vitamins and minerals are substances your body needs to help carry out important functions. They work to help your body get energy from the foods you eat, help repair tissue, and help maintain life. Therefore, they are essential for your body. But if you have kidney disease or are on dialysis, you may not be getting enough.
Does Creatine Affect The Liver
Creatine is predominantly marketed as a supplement to improve athletic performance and increase muscle mass. Clinical research studies are inconclusive about the efficacy and safety of creatine supplements however, there are some indications that high-dosage or long-term use may result in damage to the liver or other serious side effects. Consult a qualified health care provider before taking creatine.
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Creatinine Levels : What Is Considered A Bad Creatinine Level
7 Easy Ways to Lower Creatinine Levels Naturally. Alrighty here they are, what I have put together is some really easy tips you can put into practice straight away to help boost your kidney function, while having a direct impact on your creatinine blood levels. 1. Vegetarian Die Your urine creatinine levels can reveal kidney problems. Your doctor will either order a spot test when you give a small urine sample at a random time in the day or a 24h creatinine urine test. The 24h test is more accurate, as long as you carefully follow the instructions. If your levels are low, you may have kidney issues The production of natural creatine is a protein building block that is stored in your muscles and used as energy. When your kidneys are healthy, creatinine is safely removed from the body. The aim of normal creatinine levels in the blood should range between 0.6 to 1.2 mg/dL for men, and 0.5 to 1.1 mg/dL for women Creatinine is the most acute indicator of how well your kidneys are working. Since the generation of creatinine is stable, high creatinine always means your kidney fail to excrete creatinine with urine. Therefore, they are often recommended to take plenty of water to reduce creatinine. However, how much water should you drink
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What Are The Ways To Make A Kidney
If you have diabetes along with kidney disease, you need to control your blood sugar to prevent more damage to your kidneys. A diabetic diet and a kidney-friendly diet share a lot of the same food items, but there are some important differences. There are some ways your kidney-friendly diet and diabetic diet can work together. Below are a few food items that are good for you, if youre diagnosed with both diabetes and kidney disease.
- Fruits: Berries, papaya, cherries, apples and plums
- Vegetables: Cauliflower, onions and spinach
- Proteins: Lean meats , eggs and unsalted seafood
- Carbohydrates: Whole-wheat breads, sandwich buns, unsalted crackers and pasta
- Fluids: Water, clear soups and unsweetened tea
- If you drink orange juice to treat low blood sugar, switch to kidney-friendly apple juice. It will provide the same blood sugar boost with a lot less potassium.
Your doctor and/or dietician will help you to create a meal plan that helps you control your blood sugar level while limiting sodium, phosphorus, potassium and fluids in the body.
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Who Should Not Use Fish Oil
People with a high risk for the condition are found to be more likely to take Omega 3 supplements.
The study, published in the Journal of the American College of Cardiology, found that people who took at least one daily dose of fish oil supplements were more than twice as likely to have a heart attack or stroke than those who did not take the supplements, according to a press release from the University of California, San Francisco School of Medicine.
The study was conducted by researchers from UCSF and the National Heart, Lung, and Blood Institute and was funded by the U.S. Department of Health and Human Services Office of Dietary Supplements , the NHLBIs Center for Nutrition Policy and Promotion , and NIHs National Institute of Diabetes and Digestive and Kidney Diseases.
Fish oil is a type of polyunsaturated fatty acid found in fatty fish such as salmon, mackerel, sardines, anchovies, herring and tuna. Fish oil has been shown to lower blood pressure, reduce inflammation and improve heart health, the release said.
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Boosts Performance During High
A study has shown that supplementing with creatine during high-intensity interval training can help improve performance. Creatine increases the bodys production of phosphocreatine, which is an essential element in the production of energy. Phosphocreatine is also essential in improving athletic performance in exercises of different intensities at different times, such as high-intensity interval training.
In fact, researchers believe that creatine is among the most effective supplements when used for high-intensity exercise. Over 70% of studies have shown a strong positive correlation between creatine supplementation and improved performance in high-intensity exercise, while the other 30% still showed a small positive effect, meaning no negative effects have ever been discovered.
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What Does Iron Do
Iron helps your body in many ways. One way is to help make red blood cells. Red blood cells carry oxygen from your lungs to all parts of your body. They give you the energy you need for your daily activities. The kidneys tell your body to make red blood cells. Iron helps make red blood cells healthy.
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Myth : Creatine Supplementation Causes Rhabdomyolysis
Fact: There is no direct evidence that creatine supplementation promotes rhabdomyolysis.
This myth became a media favorite shortly after an article published in the New York Times claimed creatine supplementation was possibly linked to rhabdomyolysis in high school football players. Rhabdomyolysis refers to a severe breakdown of skeletal muscle due to injury that typically presents with elevated creatine kinase levels and anterior compartment syndrome. This condition can result from excessive exercise in hot humid climates, especially when the exercise is continued for several days.
According to reports, the athletes in this case were in a training camp where they performed exhaustive bouts of repetitive exercise in a hot and humid wrestling room. None of the athletes indicated they took creatine. Nevertheless, investigators speculated creatine could have caused the problem.
The suggestion that creatine supplementation induces rhabdomyolysis has no backing in scientific literature. Indeed, creatine kinase levels are elevated following supplementation, but these levels are nowhere close to the levels associated with rhabdomyolysis. Not to mention the various studies supporting the safety of creatine supplementation on hydration levels and kidney function.
If anything, creatine has been shown to have a beneficial effect on hydration by increasing water retention, lowering body temperature, and reducing exercising heart rate.
Creatine Is It Worth The Risk
- Nancy Ling, RDUpdated OnSeptember 09, 2013
- Competitor Magazine
Creatine’s first documented use was in the Soviet Union during the 1960s, when a professor of exercise biochemistry researched creatine supplementation in elite athletes. His experiments were thought to have played a role in the Soviet Union’s unprecedented success in power lifting, wrestling and gymnastics in the Olympic Games from 1964 to 1994.
Creatine is an amino acid derivative found naturally in the body. Concentrated in the muscle, it is produced by the body from amino acids and is consumed in meat and fish. It functions as an essential part of muscle contraction.
Athletes and body builders take creatine supplements to try to increase the pool of creatine in muscle, so the muscles can work harder and recover faster.
Does creatine work?
Many studies have been performed to determine the effectiveness of creatine supplementation in athletes. It has been shown to improve performance in bicycling sprints and weightlifting. Studies involving bicycle sprints found that creatine supplementation increases in total work performed. Most studies evaluating weightlifting or specific muscle group activities suggest that taking creatine helps increase lifting strength.
There is no indication that use of creatine gives any benefit in sports such as running and swimming. Studies indicate that creatine does not enhance endurance.
How much is needed?
Any side effects?
The bottom line
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Who Has Low Or High Blood Creatinine Levels
- Muscular young or middle-aged adults may have more creatinine in their blood than the norm for the general population.
- Elderly persons may have less creatinine in their blood than the norm. Infants have normal levels of about 0.2 or more, depending on their muscle development.
- In people with malnutrition, severe weight loss, and long standing illnesses, the muscle mass tends to diminish over time and, therefore, their creatinine level may be lower than expected for their age.
Creatine Is One Of The Best And Most Basic Supplements You Can Take But Some Worry About Its Long
When talking about results, creatine is one of the most basic and best supplements anyone can take. If you had to pick between something like a protein supplement and creatine, for most people Id say go with the creatine. Its that good and that proven for results.
But as with all things, although the results speak for themselves we need to make sure that supplementing with creatine is healthy as well. In general, I think supplementing with the basic nutrients like creatine is not going to be harmful, but it never hurts to research these topics at length. Quite the contrary, I think the best supplements should be scrutinized the most. In a study done by the Journal of the International Society of Sports Nutrition, thats exactly what researchers did.
The researchers looked specifically at the impact of long-term creatine use on kidney function. Just for good measure, they threw in a high protein diet along with that creatine use. It might sound like they were trying to push the limits, but in reality this is what athletes do. So, we may as well study the effect it has on our health. Long term is relative here. The study lasted for twelve weeks of creatine supplementation, but I think that was a good enough amount of time to see the necessary results.
Photo courtesy of Shutterstock.
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Our Kidneys Filter Proteins Waste Products
As our body metabolizes protein, the process generates various nitrogenous waste products such as urea, uric acid, creatinine, and hippuric acid .
These waste products need filtering out of the body for excretion, and this responsibility belongs to our kidneys.
This task requires a lot of hard work, which is quite normal for the kidneys they receive and process approximately 1.2 liters of blood per minute. This amount accounts for around 25% of all cardiac output, which shows the importance of the organ .
If waste products build up in our body, they become toxic, and so the kidneys play a crucial role in removing these products.
As a result, many people assume that higher protein intake leads to a higher kidney workload, and the extra demand causes kidney strain.
Precautions When Taking Creatine
Since creatine causes the muscles to draw water from other parts of the body, drink more fluids when taking the supplement, advises the U.S. National Library of Medicine. In addition, don’t exercise in the heat, because it can result in dehydration.
Taking creatine and caffeinated beverages, such as coffee, tea and soda, together may cause a stroke or worsening of Parkinson’s disease. Don’t take the supplement with ephedra, because it can result in a stroke or other serious consequences, says Michigan Medicine.
If you have signs of an allergy, such as hives, swelling or difficulty breathing, go to an emergency room, notes Michigan Medicine. Should you experience fluttering in your chest, a pounding heartbeat or trouble breathing, stop taking creatine and call your doctor.
Some medications, such as certain antibiotics like cyclosprine and gentamicin, can harm the kidneys. Non-steroidal anti-inflammatory drugs like ibuprofen and indomethacin can also harm the kidneys. The U.S. National Library of Medicine warns that taking creatine with these drugs increases the likelihood of kidney damage.
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Is Creatine Bad For You
The dangers of creatine include kidney damage, weight gain and dehydration. Other side effects include, but are not limited to, diarrhea, nausea and seizures.
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Experts believe creatine is safe for most people at recommended doses for short-term use. However, it has side effects, and its long-term safety isnât known.
Low And High Creatinine Levels
Usually, low creatinine means that there is too little creatine being produced in the body. This state will relate to the liver, muscles, or diet.
High levels of creatinine usually mean that there is too much creatine in the body, or that creatinine is not being filtered and removed from the body properly.
Creatinine levels often rise during intense exercise, as more creatine is burned for energy, or because someone may eat a high-protein diet.
High levels could also indicate a problem with the kidneys, as these organs get rid of waste products from the body to keep the blood clean.
- Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. . Creatine supplementation with specific view to exercise/sports performance: An update. Journal of the International Society of Sports Nutrition, 9
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How Safe Is Creatine
Just because creatine is natural, doesnt necessarily mean that it is safe. Supplements arent held to the same standards by the FDA as medications, which means you cant always know exactly whats in your supplement, or in what amounts.
Researchers still dont know the long-term effects of taking creatine supplements, especially in young people. Adolescents who take creatine often do so without their doctors advice, which can cause them to take more than the recommended dose.
Although most healthy people can take it with no problem, creatine can, in rare cases, have adverse effects, particularly when used in excess. Side effects can include:
- Weight gain
- Stomach upset
Taking the stimulants caffeine and ephedra with creatine can increase the risk of side effects.
Creatine isnt recommended for people with kidney or liver disease, or diabetes. Others who should avoid taking it are children under age 18 and women who are pregnant or nursing. Also dont use creatine if you are taking any medication or supplement that could affect your blood sugar, because creatine may also affect blood sugar levels.
If you do take creatine, drink enough water to prevent dehydration.
No matter how healthy you are, let your doctor know before you take creatine or any other supplement.
Negative Effects Of Preworkouts
Preworkout supplements are one way for weight lifters and fitness fanatics to get energized for high-intensity workouts. The stimulants in these supplements provide a boost for your muscles and energy level, but they can also lead to a number of negative side effects including dehydration, kidney problems and high blood pressure.
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Normal Blood Creatinine Range
Creatinine levels increase with muscle mass. Other factors, such as age, sex, ethnicity, diet, etc., also affect its production .
The normal blood creatinine range is around:
- Men: 0.6 to 1.2 mg/dL 53 to 106 mol/L
- Women: 0.5 to 1.1 mg/dL 44 to 97 mol/L
Levels may vary slightly between labs, due to differences in equipment, techniques, and chemicals used.
A normal test doesnt mean that kidney disease is absent. Your doctor will interpret your results in conjunction with your medical history and other test results, such as glomerular filtration rate , blood urea nitrogen , phosphate, calcium, sodium, potassium, and glucose.
What Analgesics Are Safe For People Who Have Kidney Disease
Acetaminophen is the drug often recommended for occasional use in patients with kidney disease. But everyone with kidney disease should rely on their doctor or other health care professional for a personal recommendation. It is important to know that any drug can be harmful if used at high doses or very frequently. People with kidney disease should also be sure to avoid drinking alcohol while taking pain medicines.
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