Sunday, May 19, 2024
HomeEditor PicksWhat Is The Most Common Cause Of Acute Kidney Failure

What Is The Most Common Cause Of Acute Kidney Failure

What Is The Treatment For Acute Kidney Failure

Acute Renal Failure: Most common causes

Your treatment will depend on the cause of your acute kidney failure. The goal is to restore normal kidney function. Preventing fluids and wastes from building up in your body while your kidneys recover is important. In the majority of cases, a kidney specialist called a nephrologist makes an evaluation.

Acute Kidney Failure Postrenal Causes

Postrenal failure is sometimes referred to as obstructive renal failure, since it is often caused by something blocking elimination of urine produced by the kidneys. It is the rarest cause of acute kidney failure . This problem can be reversed, unless the obstruction is present long enough to cause damage to kidney tissue.

Obstruction of one or both ureters can be caused by the following:

  • Kidney stone, usually only on one side
  • Cancer of the urinary tract organs, kidney cancer or tumor, or structures near the urinary tract that may obstruct the outflow of urine
  • Medications
  • Bladder stone
  • Bladder cancer
  • Neurologic disorders of the bladder impairing its ability to contract

Treatment consists of relieving the obstruction. Once the blockage is removed, the kidneys usually recover in 1 to 2 weeks if there is no kidney infection or other problem.

Studies On Coronavirus And Kidney Disease Show That Hospitalized Covid Patients Are In Big Danger Of Developing Acute Kidney Injury

Various studies show an undeniable connection between COVID-19 and AKI. Some studies show that 4%37% of coronavirus cases are linked to the kidneys and that AKI is prevalent among 50% of hospitalized patients.

Other reviews say that 10% of patients with a severe covid diagnosis will develop AKI, while a study from September 2020 showed the figure was as high as 81%. Although the numbers are different in each study, the link between the two is pretty obvious.

Recommended Reading: Is Watermelon Bad For Kidneys

Kidney Failure Urine Color

The color of your urine is a small window into your bodys health. It doesnt tell you much about the state of your kidney function until damage to the kidneys has progressed.

Still, urine color changes may be a warning sign of some issues.

  • Clear or pale yellow.Clear or pale yellow urine indicates youre well hydrated. This is the ideal color in most cases.
  • Dark yellow or amber. You may be dehydrated. Try drinking more water and cutting down on dark sodas, tea, or coffee.
  • Orange. This could be a sign of dehydration, or it might be a sign of bile in your bloodstream. Kidney disease doesnt typically cause this.
  • Pink or red. Urine with a pink tint or a bit of red could have blood in it. It could also be caused by certain foods, like beets or strawberries. A quick urine test can tell the difference.
  • Foamy. Urine with excess bubbles is a sign that it likely has a lot of protein in it. Protein in urine is a sign of kidney disease.

Urine color can raise flags for potential problems. Learn about the common color causes and whats most likely to affect the shade of your pee.

Kidney failure can be the result of several conditions or causes. According to the National Kidney Foundation, the two most common causes are high blood pressure and diabetes.

People who are most at risk usually have one or more of the following.

Pearls And Other Issues

Acute Renal Failure

Mild AKI can often be managed on an outpatient basis. AKI, more often than not, is a co-existent problem for hospitalized patients. It is usually appropriate for these patients to be on the general medical floor unless they also have an electrolyte imbalance or significant volume overload, in which case, they may require a higher level of care. The most important issues to realize for clinicians dealing with AKI are adjusting the dose of any medications these patients are taking and avoiding nephrotoxic medications as much as possible. The other important factor to consider is an appropriate fluid challenge whenever possible.

Don’t Miss: Is Ginger Good For Kidney Patients

How Is Kidney Failure Diagnosed

Doctors use a variety of tests to measure kidney function and diagnose kidney failure. If your doctors suspect you may be at risk for kidney failure, they may recommend:

  • Blood tests, which can show how well the kidneys are removing waste from the blood.
  • Advanced imaging, which can show kidney abnormalities or obstructions .
  • Urine tests, which measure the amount of urine or specific substances in the urine, such as protein or blood.

Ckd Is More Frequent Among Women Than Men

Chronic kidney disease among the adult US population is more common in women than men . Women struggle more often with CKD because they get urinary tract infections more often than men. Likewise, pregnancy, high blood pressure, and eclampsia can also be the risk factors that can lead to kidney damage.

That said, when it comes to chronic kidney disease prevalence by age, CKD is much more prevalent among people older than 65 years 38%, compared to people between the ages of 45 and 64 13%, and people between 18 and 44 7%.

Read Also: Aleve Effect On Kidneys

How Is Aki Diagnosed

When a patient shows sudden high levels of creatinine in the blood, it is likely that the patient is experiencing acute kidney injury. Doctors will use clinical context to rule out other similar conditions, such as chronic kidney disease. Usually, if the patient has been showing abnormal creatinine levels for a while and has co-occurring conditions such as hypertension and diabetes, they are more likely have chronic kidney disease.

Once AKI is diagnosed, doctors will try to find the underlying cause in order to treat it. Sometimes, the underlying cause is easily identifiable because it correlates with another major condition that may have led to blood loss or infection .

If your doctor suspects that you might have acute kidney injury, he or she might perform the following tests:

What Happens If Kidney Failure Is Untreated

Acute kidney failure – What is the most common cause of acute kidney failure? |

Left untreated, kidney infections can lead to permanent kidney damage. Over time, severely damaged or scarred kidneys can increase the risk of kidney failure, a condition in which the kidneys no longer function properly. Individuals with kidney failure may require dialysis, also referred to as artificial kidney treatments.

Also Check: Ginger Good For Kidney

Symptoms Of Kidney Failure

The kidneys are responsible for ridding the body of wastes, toxins, and excess fluids while returning hormones, glucose , minerals, and other important substances to the bloodstream.

When the kidneys fail, fluids, waste, and other substances can accumulate to harmful levels. At the same time, hormones normally produced by the kidneys can plummet due to the damage to the kidneys themselves. Both effects account for many of the symptoms of kidney failure.

Common symptoms include:

In severe cases, the accumulation of waste and toxins can lead to seizures and even coma.

Treating Acute Kidney Injury

Treatment of AKI depends on what’s causing your illness and how severe it is.

You may need:

  • to increase your intake of water and other fluids if you’re dehydrated
  • antibiotics if you have an infection
  • to stop taking certain medicines
  • a urinary catheter, a thin tube used to drain the bladder if there’s a blockage

You may need to go to hospital for some treatments.

Most people with AKI make a full recovery, but some people go on to develop chronic kidney disease or long-term kidney failure as a result.

In severe cases, dialysis, where a machine filters the blood to rid the body of harmful waste, extra salt and water, may be needed.

Recommended Reading: Watermelon Good For Kidneys

Common Causes Of Kidney Disease According To Nephrologists

Your kidneys may be small, but boy, are they crucial. Their job is to remove waste and excess fluid from your blood. They also control the amount of nutrients in your body such as sodium, potassium, phosphorous, and calcium: all key to keeping your vital functions going.

When your kidneys are in balance, they are a well-oiled machine. But other health conditions can cause them to veer off course, and, if they’re left untreated, can ultimately progress to kidney failure, says Cassandra Kovach, MD, a nephrologist at the Cleveland Clinic. “The two main causes of chronic kidney disease are high blood pressure and diabetes, both of which are often preventable,” she explains. .

Here’s a look at some of the most common causes of kidney disease and how you can protect against them.

Acute Kidney Injury Network Classification System

Journal club.......

The Acute Kidney Injury Network has developed specific criteria for the diagnosis of AKI. The AKIN defines AKI as abrupt reduction of kidney function, manifested by any 1 of the following :

  • An absolute increase in serum creatinine of 0.3 mg/dL or greater
  • A percentage increase in serum creatinine of 50% or greater
  • A reduction in urine output, defined as less than 0.5 mL/kg/h for more than 6 hours

AKIN has proposed a staging system for AKI that is modified from RIFLE. In this system, either serum creatinine or urine output criteria can be used to determine stage. See Table 2, below.

Table 2. Acute Kidney Injury Network Classification/Staging System for AKI


Increase of 0.3 mg/dL or 1.5- to 2-fold increase from baseline

< 0.5 mL/kg/h for > 6 h

> 2-fold to 3-fold increase from baseline

< 0.5 mL/kg/h for > 12 h

> 3-fold increase from baseline, or increase of 4.0 mg/dL with an acute increase of at least 0.5 mg/dL

< 0.3 mL/kg/h for 24 h or anuria for 12 h

*Patients who receive renal replacement therapy are considered to have met the criteria for stage 3 irrespective of the stage they are in at the time of RRT.

You May Like: Watermelon For Kidneys

Acute Kidney Failure Prognosis

Recovery from acute kidney failure depends on what caused the disease. If the cause does not stem from damage to kidney tissue itself, the prognosis is good and the patient will probably make a full recovery. Partial recovery of renal function may occur in situations in which the injury does not completely resolve. In general, the more ill a patient is during the onset of renal failure, the worse the outcome. Severe cases of acute renal failure can result in death.

On long-term follow-up , approximately 12.5% of survivors of acute renal failure require dialysis and 19% to 31% of them have chronic kidney disease.

The in-hospital mortality rate for acute kidney failure is 40% to 50%.

The mortality rate in patients in intensive care settings with acute kidney failure that requires dialysis is 70% to 80%.

What Are The Symptoms Of Aki

In milder forms of AKI, there may not be any signs or symptoms and your doctor may find it when doing tests to look for other things.

In more severe forms of AKI, signs and symptoms may include:

  • Urinating less often
  • Swelling in your legs, ankles or feet
  • Feeling weak and tired
  • Feeling like you cannot catch your breath
  • Feeling confused
  • Feeling sick to your stomach
  • Feeling pain or pressure in your chest
  • Seizures or coma

If you notice a combination of any of these symptoms, talk to your doctor.

Read Also: Is Ibuprofen Metabolized In The Kidneys Or Liver

Acute Kidney Failure Renal Causes

Primary renal damage is the most complicated cause of renal failure . Renal causes of acute kidney failure include those affecting the filtering function of the kidney, those affecting the blood supply within the kidney, and those affecting the kidney tissue that handles salt and water processing.

Examples of kidney problems that can cause kidney failure include:

  • Blood vessel diseases
  • Blood clot in a vessel in the kidneys
  • Injury to kidney tissue and cells
  • Glomerulonephritis
  • Polycystic kidney disease

Glomerulonephritis: The glomeruli, the initial filtration system in the kidney, can be damaged by a variety of diseases, including infections. The resulting inflammation impairs kidney function.

  • A common example is a complication of strep throat. Streptococcal bacterial infections may damage the glomeruli.
  • Glomerular disorder symptoms may include dark-colored urine and back pain.
  • Other symptoms include producing less urine than usual, blood in the urine, high blood pressure, and body swelling .
  • Treatment usually consists of medications and, if kidney function fails significantly, dialysis may be needed to remove life-threatening waste products that cannot be excreted.

Acute interstitial nephritis: This is a sudden decline in renal function caused by inflammation of interstitial kidney tissue that primarily handles salt and water balance rather than the filtering of wastes.

How Common Is Esrd

Renal causes of kidney failure – the Acute Kidney Injury series

Not everyone with chronic kidney disease will develop ESRD. Of the 37 million people living with CKD in the United States, around 786,000 have ESRD. Comparatively, men are 50% more likely to get ESRD than women, while Black people are 3 times more like to get ESRD than White people.

Don’t Miss: Aleve Side Effects Kidney

How Is Aki Treated

Treating AKI depends on the underlying cause of the condition. If it is caused by medications, your doctor may ask you to stop taking that specific medication. If its caused by an infection, your doctor may look for ways to treat the infection.

In more serious cases, when there are life-threatening changes in fluids, electrolytes, or acid-base balance in your body, your doctor may put you on dialysisa machine that does the kidneys job for you while your kidneys recover.

Acute Kidney Failure Medications

The patient may be given medicines to treat the cause of the acute renal failure or to prevent complications.

  • Antibiotics: To prevent or treat infections
  • Diuretics : Quickly increase urine output
  • Other medications: To get rid of extra fluid and prevent electrolyte imbalances
  • Kayexalate is used to decrease buildup of potassium
  • Sodium bicarbonate is used to decrease acid buildup
  • Don’t Miss: Is Pomegranate Juice Good For Your Kidneys

    Acute Kidney Failure Prevention

    You can reduce your risk of getting acute kidney failure by practicing some healthy habits.

    • Be careful when taking over-the-counter pain medications. Whether you are taking NSAID medications like aspirin, ibuprofen, and naproxen or other types of OTC pain medications like acetaminophen, itâs important to read and follow the recommended dosing instructions on the package. If you take too much of these meds, you could increase your chances of getting acute kidney failure.
    • Follow your doctorâs advice. If you have a higher risk of getting acute kidney failure because of pre-existing kidney disease or other conditions, make sure to follow your doctor’s advice for treating and managing your condition.
    • Keep a healthy lifestyle. Exercise, eating right, and drinking little or no alcohol can go a long way to preventing acute kidney failure.

    Show Sources

    Causes Of Kidney Failure

    C for Chocolate: January 2014

    March is National Kidney Month, making now the perfect time to look at some of the things that can lead to kidney failure, which is also called end-stage renal disease . According to the National Institute of Diabetes and Digestive and Kidney Diseases , each year there are over 117,000 new cases of ESRD each year. There are several conditions that may lead to end-stage renal disease. Some conditions cause kidney damage over time, while others act more quickly. This list is not complete by any means, but it covers the basics.

    Also Check: Is Apple Cider Vinegar Good For The Kidneys

    What Are The Signs And Symptoms Of Acute Kidney Injury

    Signs and symptoms of acute kidney injury differ depending on the cause and may include:

    • Too little urine leaving the body
    • Swelling in legs, ankles, and around the eyes
    • Fatigue or tiredness
    • Seizures or coma in severe cases
    • Chest pain or pressure

    In some cases, AKI causes no symptoms and is only found through other tests done by your healthcare provider.

    What Are Problems With The Urinary System

    The urinary system is the organs that make urine and remove it from your child’s body. It includes the kidneys, ureters, bladder and urethra. Urine travels from their kidneys through two thin tubes called the ureters, into the bladder and then out of their body through their urethra. Two problems in the urinary system can cause kidney disease:

    • A blockage in the urinary system
    • Urine reflux

    Read Also: Is Apple Cider Vinegar Bad For Kidney Disease

    What Is Nephrotic Syndrome

    Nephrotic syndrome is a group of symptoms that show that your child’s kidneys are not working as well as they should. The symptoms include:

    • Not enough protein in their blood
    • Too much fat or cholesterol in their blood
    • Swelling in their legs, feet, ankles and sometimes face and hands

    Your child may start to have symptoms between ages two and six.

    The most common causes of nephrotic syndrome in children are diabetes and minimal change disease.

    Acute Kidney Failure Follow

    Understanding acute kidney injury â Online interview

    The doctor will arrange follow-up visits as needed for the underlying cause of the kidney failure and the severity of the disease. Underlying condition will be monitored and appropriate lab tests will be performed to be sure that the kidney failure has resolved. Preventive measures may be needed in some situations to prevent the problem from occurring again.

    You May Like: Kidney Stone Sonic Blast Treatment

    Acute Kidney Failure Prerenal Causes

    Prerenal failure is the most common type of acute renal failure . The kidneys do not receive enough blood to filter. Prerenal failure can be caused by the following conditions:

    • Dehydration: From vomiting, diarrhea, water pills, or blood loss
    • Disruption of blood flow to the kidneys from a variety of causes:
    • Drastic drop in blood pressure after surgery with blood loss, severe injury or burns, or infection in the bloodstream causing blood vessels to inappropriately relax
    • Blockage or narrowing of a blood vessel carrying blood to the kidneys
    • Heart failure or heart attacks causing low blood flow
    • Liver failure causing changes in hormones that affect blood flow and pressure to the kidney

    There is no actual damage to the kidneys early in the process with prerenal failure. With appropriate treatment, the dysfunction usually can be reversed. Prolonged decrease in the blood flow to the kidneys, for whatever reason, can however cause permanent damage to the kidney tissues.


    Most Popular