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Can Diabetes Cause Kidney Cancer

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Mayo Clinic Explains Kidney Disease

This is a common misconception the kidney and liver are the primary organs in the body that remove byproducts of metabolism, often referred to as toxins in the body, Coyle says. These byproducts are excreted by the body in our urine. Sweat in the underarms is not a biological pathway to rid the body of toxins.

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About Kidney Cancer: Symptoms Causes And Assessing Your Risk

Elizabeth Plimack, MD, MS is proud to be a part of a team of distinguished researchers who have pioneered many of these new treatments. Her particular research efforts focus on the development of new therapies for bladder and kidney cancer.

Kidneys clean the blood to filter out waste and produce urine. They also make hormones that help control blood pressure and signal for bone marrow to make red blood cells when needed.

Almost all kidney cancers are carcinomas, which start in cells that line the inner or outer surfaces of the body. In the kidneys, carcinomas most often start in the lining of the renal tubules, which remove excess water and waste from the blood to make urine. This is called renal cell carcinoma, which accounts for more than 90 percent of kidney cancer. Kidney cancer is often found before it spreads, but left undetected, it can grow and spread to other organs.

Less common types of kidney cancer include:

  • Transitional cell carcinoma, which starts in the cells that line the renal pelvis
  • Wilms tumors, which almost always occurs in young children
  • Renal sarcoma, which starts in the blood vessels or connective tissue of the kidneys
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    How Serious Is A Tumor On The Kidney

    It depends. Some kidney tumors are benign . These tumors are generally smaller than cancerous tumors and dont spread to other parts of your body. Surgical removal is the most common treatment for noncancerous kidney tumors.

    Whether your kidney tumor is cancerous or noncancerous, you should move forward with treatment as soon as possible to avoid complications.

    The Mechanism Is Unknown

    Chronic Kidney Disease Can Cause Diabetes, Study Finds  MDSource

    It is clear that diabetes can lead to kidney disease, but just why high blood sugars should damage the glomeruli is unclear. High blood pressure is a known risk factor for kidney disease and people with diabetes are prone to hypertension. The renin-angiotensin system â which helps regulate blood pressure â is also thought to be involved in the development of diabetic nephropathy.Other risk factors include cigarette smoking and family history. Diabetic nephropathy progresses steadily despite medical intervention. However, treatment can significantly slow the rate of damage.

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    Aluminum And Kidney Disease

    The FDA requires aluminum-based deodorant manufacturers to include a warning label for people living with kidney disease stating Ask a doctor before use if you have kidney disease. This advisory is for people living with kidney disease whose kidneys are functioning at 30% or less . Typically, aluminum found in your body is filtered through your kidneys. If your kidneys are not fully functioning, they may not be able to effectively filter out all aluminum from your body.

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    Diabetes Not A Major Driver Of Oncologic Outcomes In Renal Cell Carcinoma

    Diabetes mellitus does not play a major role in survival from renal cell carcinoma , according to data presented at the 22nd annual meeting of the Society of Urologic Oncology.

    Diabetes mellitus has been hypothesized to be a risk factor for development of renal cell carcinoma, Ava Saidian, MD, of the University of California, San Diego, explained.

    To test this theory, her team retrospectively analyzed survival outcomes from 2927, 2513, and 460 patients with stage 1, 2, and 3 RCC, respectively, from the International Marker Consortium for Renal Cancer . Of these groups, 24%, 27%, and 77% had diabetes, respectively.

    According to Kaplan Meier analyses, diabetes status had no significant relationship with cancer-specific mortality or progression-free survival at any RCC stage, Dr Saidian reported. Only patients without diabetes mellitus had significantly increased risks of all-cause mortality in stage 1 and 3 RCC, a Cox Regression multivariable analysis showed.

    Tumor size, male sex, and hypertension were significantly associated with 1.1-, 1.4-, and 1.7-fold increased risks for all-cause mortality, respectively.

    Our findings suggest that may have impact on survival in RCC, but this impact is mostly driven by non-oncologic as opposed to oncologic effects, Dr Saidian concluded.


    This article originally appeared on Renal and Urology News

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    Association Between Diabetes And The Risk Of Kidney Cancer: Systematic Review And Meta

    Clin Diabetes

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  • Andrés Bonilla-Sanchez, Jenny Rojas-Munoz, Herney Andrés Garcia-Perdomo Association Between Diabetes and the Risk of Kidney Cancer: Systematic Review and Meta-Analysis. Clin Diabetes 1 July 2022 40 : 270282.

    Diabetes is a risk factor for several types of cancer, but the specific relationship between diabetes and kidney cancer is not well understood. We conducted a search strategy in scientific databases for case-control and cohort studies on this topic. We analyzed 17 studies and found that diabetes was significantly associated with the risk of developing kidney cancer and that this risk was slightly stronger for women and for people living in Asia. These findings were not influenced by obesity, cigarette smoking, or hypertension. We conclude that diabetes is an independent risk factor for the development of kidney cancer.

    How Kidneys Recover From Alcohol Damage

    Pyelonephritis (Kidney Infection) | Causes, Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

    Acute kidney damage caused by binge drinking will typically resolve within a few days. The damage can usually be reversed if you stop drinking and allow your kidneys to recover, but it can sometimes cause irreversible damage to the kidneys.

    Regular heavy drinking can eventually cause CKD, which can lead to kidney failure. Theres no cure for CKD, but treatment can help relieve symptoms and keep it from getting worse.

    Once you have kidney failure, you may require a kidney transplant. Heavy drinking makes it more difficult for you to qualify for a kidney transplant.

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    Increase The Risk Of Diabetes

    Not only can high amounts of sugar lead to unhealthy weight gain, but it can also put you at risk of diabetes. Sugar is indirectly associated with Type 2 diabetes due to the association between high sugar consumption and obesity.

    According to the Scientific Advisory Committee on Nutrition , high amounts of sugar lead to obesity, one of the major contributors to Type 2 diabetes.

    Although prevailing theories show the indirect link of sugar to diabetes, Stanford Medicine discovers the direct association between the two factors.

    In a study between diabetes rates and sugar supply, results show that diabetes rates surged with the increase of sugar supply in a population.

    If you still like to try some mass gainers, read the label and select one that offers a great mix of fat, protein, and carbohydrates.

    Some of these brands offer very high calories, so you should make modifications to the serving size so that you conform to your calorie requirements for weight increase. You must check your blood sugar weekly to determine any changes in your blood sugar levels.

    What Are Common Symptoms Of Having A Mass On Your Kidney

    Having a mass or tumor on a kidney is often accompanied with other symptoms such as bloody urine, appetite loss, flank pain, weight loss and fatigue, states It can also cause anemia and swelling in the limbs.

    If the mass on the kidney is a malignant tumor and the cancer has spread to other organs, common symptoms include shortness of breath, bone pain and coughing blood, explains Before a doctor can determine if a kidney mass is cancer, tests must be done to diagnose the disease such as blood and urine tests, a CT scan and MRI, and a renal arteriogram, If the mass is a tumor, the size determines the stage of kidney cancer. For instance, a mass smaller than 3 inches is stage 1 cancer and more treatable than a mass that has spread to the tissue around the kidney.

    The mass can be removed depending on the size, states A patient with a tumor that is smaller than 1 1/2 inches can undergo a partial nephrectomy in which just the mass and some of the surrounding tissue is removed. Larger masses require removal of the entire kidney or even the nearby adrenal gland and lymph nodes. In some cases, the tumor is treated with extreme cold or radio waves.

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    Tips To Keep Your Kidneys Healthy

    You can help keep your kidneys healthy by managing your blood sugar, blood pressure, and cholesterol levels. This is also very important for your heart and blood vesselshigh blood sugar, blood pressure, and cholesterol levels are all risk factors for heart disease and stroke.

    Physical activity can help

    • Take your medicines as directed.

    How Is Kidney Cancer Treated

    Causes &  Symptoms of Kidney Stone

    Kidney cancer treatment depends on the stage and grade of the tumor, as well as your age and overall health. Options include surgery, ablation, radiation therapy, targeted drug therapy, immunotherapy and sometimes chemotherapy.


    Surgery is the treatment of choice for most stages of kidney cancer. Several surgical options may be considered, including:

    • Partial nephrectomy: Your surgeon removes the part of your kidney that contains the tumor.
    • Radical nephrectomy: Your surgeon removes your entire kidney and some of the tissue around it. They may also remove some lymph nodes in the area.

    When one kidney is removed, the remaining kidney is usually able to perform the work of both kidneys.


    Sometimes, heat and cold can destroy cancer cells. People who arent candidates for surgery may benefit from cryoablation or radiofrequency ablation.

    • Cryoablation: During this procedure, your healthcare provider inserts a needle through your skin and into the kidney tumor. The cancer cells are then frozen with cold gas.
    • Radiofrequency ablation: Your healthcare provider inserts a needle through your skin and into the kidney tumor. Next, an electrical current is passed through the cancer cells to destroy them.

    Radiation therapy

    Your healthcare provider may recommend radiation therapy if you only have one kidney or if youre not eligible for surgery. Radiation therapy is most often used for easing kidney cancer symptoms, such as pain.

    Targeted drug therapy



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    Diabetes Oral Medication Not Working

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    How Can Gout Contribute To Kidney Disease

    There is evidence that gout can lead to kidney disease, although the connection is less established. Gout happens when there is a great amount of uric acid crystallizing, resulting in joint inflammation. These crystals technically consisted of sodium urate, but they are generally referred to as uric acid crystals. Crystals often appear in the joints, but they also accumulate in the outer ear, the skin near the joints, and the kidneys.

    The crystals can cause damage and scars as they pass through the kidneys. This damage to the kidneys is thought to contribute to kidney disease and failure over time, especially if the gout is left untreated. However, some people with high concentrations of uric acid levels in the blood do not develop gout and even when they do, they can go for years without manifesting any symptoms.

    Uric acid can still build up in the body even with normal kidney function. If the kidneys couldnt filter uric acid effectively, uric acid can accumulate in the blood, which can lead to gout.

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    Type 2 Diabetes Mellitus And Kidney Cancer Risk: A Retrospective Cohort Analysis Of The National Health Insurance

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      Affiliations Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Division of Environmental Health and Occupational Medicine of the National Health Research Institutes, Zhunan, Taiwan

    How Does Diabetes Cause Kidney Disease

    Kidney Saving Diet Advise! Prevent Diabetic Chronic Kidney Disease

    High blood glucose, also called blood sugar, can damage the blood vessels in your kidneys. When the blood vessels are damaged, they dont work as well. Many people with diabetes also develop high blood pressure, which can also damage your kidneys. Learn more about high blood pressure and kidney disease.

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    How Can I Manage My Diabetes During Cancer Treatment

    Talk to your health care team about how to manage your diabetes during cancer treatment. They can provide information, monitor your health, and help you find the best support and resources that you need.

    Follow a healthy eating plan. Eating healthy, well-timed meals helps keep your blood sugar balanced. Eating well also gives your body essential nutrients it needs during cancer treatment. An oncology dietitian can help you develop an eating plan based on your health issues and needs.

    Get regular exercise. Exercise during cancer treatment helps your body use blood sugar. Physical activity can also help you stay at a healthy weight, which is an important part of managing diabetes.

    Track your health. Use a journal or a free app like Cancer.Net Mobile to track your cancer treatments, your blood sugar level, diabetes medications, other medications, and side effects. This information can help you and your doctor pinpoint any health issues and their causes.

    Manage stress. Stress from cancer and its treatments can cause your body to release various hormones that increase blood sugar. This can weaken your immune system. Stress management strategies can help you feel more relaxed and less anxious.

    Good Control Of Your Blood Pressure

    Strict blood pressure control is likely to reduce the risk of developing cardiovascular diseases and prevent or delay the progression of kidney disease. Most people should already be taking an ACE inhibitor or AIIRA . These medicines lower blood pressure.

    However, if your blood pressure remains at 130/80 mm Hg or more then one or more additional medicines may be advised to lower your blood pressure to below this level.

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    Diagnosis And What To Discuss With Your Doctor

    Youll need to have a biopsy before a diagnosis of kidney lymphoma can be confirmed. You might have a biopsy done on just your kidney or on your lymph nodes and bone marrow as well. Your doctor will let you know what tests are needed.

    It helps to know what to expect if you receive a cancer diagnosis. These questions should help you start to understand your diagnosis and what comes next:

    • What is the stage of my kidney lymphoma?
    • What exactly does that stage mean in my case?
    • What are my treatment options?
    • Why is the doctor recommending those options?
    • What are the potential risks and side effects of those treatment options?
    • What would happen if I did not pursue treatment or waited to pursue treatment?
    • How long will treatment take?
    • Will treatment impact my daily life?
    • What happens if these treatments do not work?
    • Are there any financial resources available to help pay for treatment?
    • Are there any mental health resources available?

    treatment plan for your kidney lymphoma depends on multiple factors, including the stage at diagnosis and your overall health. Treatment options might include:


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