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Does High Blood Pressure Cause Kidney Failure

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Diabetes and high blood pressure are the most common causes of kidney disease

Adults with high blood pressure, diabetes, or both, have a higher risk of developing chronic kidney disease than those without these diseases.

CKD is a condition in which the kidneys are damaged or cannot filter blood as well as healthy kidneys for 3 months or longer. Because of this, excess fluid and waste from the blood remain in the body and may cause other health problems.The good news is that there is a lot you can do to prevent kidney problems, including keeping your blood pressure and blood sugar under control.

In addition to managing blood pressure and blood sugar levels, managing cholesterol levels is very important because these are all risk factors for heart disease and stroke.

How To Prevent Or Slow Ckd

The best way to prevent CKD is to manage and treat conditions, such as diabetes and high blood pressure, that can damage your kidneys. Lifestyle changes, such as maintaining a healthy weight and not smoking, can also help. If you are at risk for CKD, talk to your doctor about how often you should get screened for the condition. Early detection and treatment are important in helping prevent CKD from progressing.

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High Blood Pressure Causes Kidney Damage

High blood pressure can constrict and narrow the blood vessels in your kidneys, which reduces blood flow and stops the kidneys from working well. When this happens, the kidneys are not able to remove all wastes and extra fluid from your body. Extra fluid in the blood vessels can raise your blood pressure even more, creating a dangerous cycle, and cause more damage leading to kidney failure.

  • More than 1 in 7 adults in the US, or about 37 million people, may have chronic kidney disease
  • High blood pressure is the second leading cause of kidney failure in the US after diabetes
  • Approximately 1 in 5 adults in the US with high blood pressure may have CKD
  • Although Black or African American people make up about 13 percent of the population, they account for 35 percent of the people with kidney failure in the United States. These numbers are concerning and reflect some of the nonmedical reasons for the increased rates of high blood pressure in communities of color, which include where someone lives and works, the foods they eat, how much exercise they do, and if they are able to get the medical care they need.
  • High blood pressure and the early stages of CKD usually does not cause any physical symptoms, which is an important reason to have regular blood pressure screenings
  • Following a healthy diet and taking medicine for high blood pressure may keep CKD from getting worse and may prevent other health problems such as heart disease

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Men In Study Are Part Of Larger Vietnam Registry

The 316 men taking part in the Vietnam Era Twin Study of Aging are part of a larger group of volunteers who make up the Vietnam Twin Registry. The total registry contains data on some 7,000 middle-aged male twin pairs, all of whom served in the U.S. military during the Vietnam War. All the men served between 1964 and 1975.

Managed by VAs Seattle-based Epidemiologic Research and Information Center, the registry is among the largest twin registries in the nation, with members in all 50 states. It was initially formed to help answer questions about the long-term health effects of service in Vietnam, but today it serves as a resource for studies on a wide range of mental and physical health conditions.

McEvoy and Kremens team received support from the National Institutes of Health and VA. Besides VA, participating institutions were the UCSD, Boston University, and the University of Southern California.

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Can High Blood Pressure Cause Kidney Disease

Kidneys use blood vessels to clean your blood of wastes, toxins and excess fluid. High blood pressure means that high pressure is consistently being exerted against the walls of arteries throughout the body, which can damage blood vessels over time. Damage to blood vessels, including the hardening and narrowing of arteries around the kidneys, can prevent your kidneys from cleaning bloodeventually leading to kidney disease.

Kidney disease or kidney failure due to high blood pressure may take years to develop. If you are diagnosed with kidney disease, its important to know that there are things you can do to manage CKD and thrive.

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How diabetes and hypertension can lead to chronic kidney disease

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How Does Eating Diet And Nutrition Affect High Blood Pressure And Kidney Disease

Following a healthy eating plan can help lower your blood pressure. Reducing the amount of sodium in your diet is an important part of any healthy eating plan. Your health care professional may recommend the Dietary Approaches to Stop Hypertension eating plan. DASH focuses on fruits, vegetables, whole grains, and other foods that are healthy for your heart and lower in sodium, which often comes from salt. The DASH eating plan

  • is low in fat and cholesterol
  • features fat-free or low-fat milk and dairy products, fish, poultry, and nuts
  • suggests less red meat, sweets, added sugars, and sugar-containing beverages
  • is rich in nutrients, protein, and fiber

A registered dietitian can help tailor your diet to your kidney disease. If you have congestive heart failure or edema, a diet low in sodium intake can help reduce edema and lower blood pressure. Reducing saturated fat and cholesterol can help control high levels of lipids, or fats, in the blood.

People with advanced kidney disease should speak with their health care professional about their diet.

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Blood Pressure Drugs May Cause Kidney Damage Study Suggests

Kidney researcher Maria Luisa S. Sequeira-Lopez, MD, is part of the Department of Pediatrics and UVAs Child Health Research Center.

New kidney research from the School of Medicine is raising concerns that long-term use of drugs commonly prescribed to treat high-blood pressure and heart failure could be contributing to kidney damage.

Patients should continue taking the medications, which include the well-known and widely used ACE inhibitors, the researchers say. But the scientists are urging studies to better understand the drugs long-term effects.

Our studies show that renin-producing cells are responsible for the damage. We are now focusing on understanding how these cells, which are so important to defend us from drops in blood pressure and maintain our well-being, undergo such transformation and induce kidney damage, said Maria Luisa Sequeira-Lopez, MD, of UVAs Department of Pediatrics and Child Health Research Center. What is needed is to identify what substances these cells make that lead to uncontrolled vessel growth in the kidney.

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High Blood Pressure And Chronic Kidney Disease

Blood pressure is the pressure of blood pushing against the walls of your arteries. Arteries carry blood from your heart to other parts of your body.

Blood pressure normally rises and falls throughout the day, but it can damage your heart and cause health problems if it stays high for a long time. Hypertension, also called high blood pressure, is blood pressure that is higher than normal.

Uncontrolled high blood pressure is the second leading cause of kidney failure in the US. Severe high blood pressure can harm kidney function over a relatively short period of time. Even mild forms of high blood pressure can damage kidneys over several years.

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It had been known since the early days of Franz Volhard and Arthur Fishberg that renal disease and renal failure occur commonly in hypertensive patients. In the study of Perera , at a time when antihypertensive medication had not yet become available, a large proportion of patients with essential hypertension wound up in renal failure. This was later ascribed to the occurrence of malignant hypertension. With the advent of effective antihypertensive medication, malignant hypertension has become much rarer. In relatively short-term trials that clearly documented the cardiovascular benefit from antihypertensive medication, few if any cases with renal failure were observed. This led to an as yet unresolved dilemma.

There are authors who made strong statements such as: there are no reported cases of benign essential hypertensive patients with normal serum creatinine levels and no proteinuria who subsequently went on to develop renal failure . On the other hand, in the US and elsewhere, but with remarkable differences between countries , a high proportion of cases reaching end-stage renal disease with hypertension and a nondiagnostic clinical course are given the diagnosis of hypertensive nephropathy in the absence of renal biopsy and other more in-depth investigations.

What was the evidence available so far and what were its shortcomings?

Eberhard Ritz Feature Editor

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