Serotonin Type 4 Receptor Agonists
Serotonin type 4 receptor agonists stimulate peristalsis and accelerate gastrointestinal transit. Shin et al. reviewed 13 randomized controlled trials on highly selective 5-HT4 receptor agonists in adults with chronic constipation and concluded that these drugs improved stool frequency and other symptoms of constipation, generally with minor neurological/psychiatric adverse events . However, the efficacy of these drugs has not yet been reported in CKD/ESKD patients. Since CKD-related constipation is often refractory, 5-HT4 receptor agonists may be used not as a sole therapy but as an additive therapy to other drugs.
Kidney Stones Symptoms And Treatments
Kidney stones are a fairly common condition that tend to affect people more during middle age . Stones can form in one or both kidneys and quite often can just pass through the urinary system undetected and without causing any pain. Sometimes large stones can get blocked and cause considerable pain called renal colic. In this instance a treatment to break up the stone or surgery may be required.
Do You Know Constipation Can Be The Reason Behind Your Urinary Tract Infection
Are you suffering from constipation and UTI at the same time repeatedly? It always makes you wonder why? Well, whether you are aware or not, but UTI or the Urinary Tract Infection is the one commonest complex situations when you suffer from a severe case of constipation. You might want to know how UTI and constipation are associated with each other.
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Signs Of A Kidney Infection
What does a kidney infection feel like? According to the NIDDK, the most common kidney infections symptoms are:
But depending on a persons age, they may not experience all of these kidney infection symptoms. Children younger than two may only experience high fever as a sign of kidney infections, the NIDDK says, and people older than 65 might only present with cognitive issues, like confusion, hallucinations, and disorganized speech.
Kidney Stone With Pain
The sharp cramping pain on either side of your lower back and nausea or vomiting that you have are because of a small stone that has formed in the kidney. Its now passing down a narrow tube on its way to your bladder. Once the stone reaches your bladder, the pain will often stop. But it may come back as the stone continues to pass out of the bladder and through the urethra. The stone may pass in your urine stream in one piece. The size may be 1/16 inch to 1/4 inch . Or, the stone may break up into sandy fragments that you may not even notice.
Once you have had a kidney stone, you are at risk of getting another one in the future. There are 4 types of kidney stones. Eighty percent are calcium stonesmostly calcium oxalate but also some with calcium phosphate. The other 3 types include uric acid stones, struvite stones , and rarely, cystine stones.
Most stones will pass on their own, but may take from a few hours to a few days. Sometimes the stone is too large to pass by itself. In that case, the healthcare provider will need to use other ways to remove the stone. These techniques include:
Lithotripsy. This uses ultrasound waves to break up the stone.
Ureteroscopy. This pushes a basket-like instrument through the urethra and bladder and into the ureter to pull out the stone.
Surgery. You may need surgery to remove the stone.
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Should You Remove Your Gallbladder You Dont Need It Anyway
The surgical removal of the gallbladder is called a cholecystectomy. This is a common procedure that with rare exception, is unnecessary and does not address the problem. Some people who have had their gallbladder removed will see absolutely no change in their symptoms while others may have their symptoms 100% resolved. Others who have had a cholecystectomy may no longer be able to eat high fat foods as their body is unable to handle too much fat digestion at once due to the removal of their bile storage tank. However, the body in its infinite wisdom can often form a new little storage pouch in the area of the common bile duct to store some bile for when its needed.
The Connection Between Constipation And Uti In Children
If your kid has been diagnosed with UTI, it is important to also check for the constipation signs. As per the studies, children suffering from chronic constipation usually also suffer from UTI. It has also been found that treatment executed fro constipation among kids helps to eliminate pyuria, enuresis, and bacteriuria.Constipation and UTI at the same time can be a big problem.The Urinary Tract Infections are caused mainly because of the bacterial or microbe infections surpassing the urinary tracts natural defensive potential. A kid with UTI might experience the following:
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How Is The Infection Spread
It is difficult to spread a UTI between individuals, as the type of bacteria causing the infection is almost never contagious.
The most common way that a UTI is contracted is through the movement of bacteria from the anus to the urethra, either when wiping after going to the toilet or during sexual intercourse. Taking care during each of these activities can help to prevent the transfer of bacteria, which may then have the opportunity to overgrow.
Vigorous sexual intercourse may also lead to symptoms of UTI or cystitis in women , although there may be no bacteria present.
Follow A Healthy Eating Plan
Many people find that alcohol spicy foods chocolate artificial sweeteners caffeinated, carbonated, and citrus beverages and high-acid foods, such as citrus and tomatoes, may contribute to bladder irritation and inflammation, which can sometimes lead to UI. You may want to avoid these foods and drinks for a time to see if your symptoms improve. A registered dietitian can help you plan meals if youre trying to avoid certain foods that make your UI worse.
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When To Seek Medical Advice
Contact your GP if you have a high temperature, persistent pain, or if you notice a change to your usual pattern of urination. Contact your GP immediately if you think your child may have a kidney infection.
If you have blood in your urine, you should always see your GP so the cause can be investigated.
Your GP can carry out some simple tests to help diagnose a kidney infection.
See diagnosing kidney infections for more information
Kidney Infection Risk Factors
Anyone can get a kidney infection. But just as women get more bladder infections than men, they also get more kidney infections.
A womanâs urethra is shorter than a manâs, and itâs closer to their vagina and anus. That means itâs easier for bacteria or viruses to get into a womanâs urethra, and once they do, itâs a shorter trip to the bladder. From there, they can spread to the kidneys.
Pregnant women are even more likely to get bladder infections. This is because of hormone changes and because a baby puts pressure on the motherâs bladder and ureters and slows the flow of urine.
Any problem in your urinary tract that keeps pee from flowing as it should can raise your chances of a kidney infection, such as:
- A blockage in your urinary tract, like a kidney stone or enlarged prostate
- Conditions that keep your bladder from completely emptying
- A problem in the structure of your urinary tract, like a pinched urethra
- Vesicoureteral reflux , which is when pee flows backward from your bladder toward your kidneys
Youâre also more likely to get an infection if you have:
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Constipation May Be A Risk Factor For Kidney Disease
Constipation is a common gastrointestinal problem that affects tens of millions of Americans. Although the condition in itself is rarely dangerous, new research suggests constipation may be a sign of poor kidney health.
Americans, according to the National Institute of Diabetes and Digestive and Kidney Diseases .
Every year, constipation accounts for visits to the doctor.
Complications are very rare, but chronic, long-lasting constipation can lead to serious health issues.
Previous research has linked constipation to an increased risk of cardiovascular disease, presumably through its effects on intestinal bacteria.
An analysis of over 70,000 women found a increased risk of cardiovascular disease in women with severe constipation.
A new study looks at the link between constipation and kidney health.
What Causes Stomach Pain
Common Causes Harmless abdominal pain usually subsides or goes away within two hours.
- Gas: Formed in the stomach and intestines as your body breaks down food, this can cause general stomach pain and cramps. This often can be indicated by belching or flatulence.
- Bloating: Related to gas, this occurs when excessive gas builds up in your digestive tract. Your stomach will usually feel full, and you may experience cramps.
- Constipation: This occurs when you are having difficulty making bowel movements. If you are having two or fewer bowel movements a week, constipation is the likely cause. In addition to feeling bloated and nauseous, you may experience cramping and pain in your rectum.
- Indigestion: You typically experience this as an upset stomach, burning, or belly pain after eating.
- Stomach flu: Your stomach may hurt before each episode of vomiting or diarrhea.
Severe Pain Causes In serious cases, the stomach pain gets worse. This may be an indication of a more severe condition, such as:
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Simple Measures To Prevent Constipation
Here are some simple steps to normalize your bowel functions:
- Increase fiber intake by adding more fruits, whole grains, and vegetables
- Drink more water and tea!
- Walk, run and exercise to be more physically active.
If you are a caregiver to an elderly person, keep in mind that when you fight constipation with too many laxatives it can lead to diarrhea and increase the chances of unhygienic conditions around the genital region, that in turn can cause urinary infections. Most infections arise from E. coli bacteria, which lives in the colon. Also, after female menopause, there is a decrease in the protective normal vaginal bacteria, so if stool bacteria gets into that area it can easily grow and travel into the bladder.
Bottom line , fight constipation! But also remember to practice good personal hygiene habits and double down on preventive methods to decrease the number of E. coli in your gut, improve vaginal health, and use D-Mannose to decrease your chances of contracting a UTI.
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Keep A Healthy Weight
If youre overweight or have obesity, losing weight may improve your UI, and keeping a healthy weight may prevent UI. If youre overweight, talk with your health care professional about how to lose weight by eating healthy and being physically active. Your chances of developing UI and other diseases and conditions, such as diabetes, increase if you have obesity. Managing obesity and diabetes may lessen UI, especially in women.7
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What Is A Kidney Stone
Kidney stones are small, hard deposits of mineral and acid salts that form on the inner surface of the kidneys, Roger Sur, M.D., director of the Comprehensive Kidney Stone Center at UC San Diego Health, tells SELF.
True to their name, kidney stones look like little pebbles that can vary in color , texture , and size , according to the National Institute of Diabetes and Digestive and Kidney Diseases . In rare nightmare scenarios, they can even reach the size of a golf ball .
Kidney stones are made of minerals normally found in your pee, like calcium, oxalate, and phosphorus, that dont cause issues at low levels, the NIDDK explains. As these minerals start to accumulate and crystalize, they can begin to stick togetheroften when the urine becomes more concentrated, the Mayo Clinic explains, which can happen due to things like dehydration.
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Ibs And Other Functional Gi Disorders
Functional gastrointestinal disorders such as irritable bowel syndrome , functional abdominal bloating and distention, functional constipation, and functional dyspepsia may cause problems with gas symptoms.
Functional GI disorders are related to problems with how your brain and your gut work together. These problems can cause you to feel more bloating or abdominal pain or can affect how gas moves through your intestines.
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When To See Your Gp
See your GP if you have a fever and persistent tummy, lower back or genital pain, or if you notice a change to your usual pattern of urination.
Most kidney infections need prompt treatment with antibiotics to stop the infection from damaging the kidneys or spreading to the bloodstream. You may also need painkillers.
If you’re especially vulnerable to the effects of an infection for example, if you have a pre-existing health condition or are pregnant, you may be admitted to hospital and treated with antibiotics through an intravenous drip.
After taking antibiotics, you should feel completely better after about two weeks.
In rare cases, a kidney infection can cause further problems. These include blood poisoning and a build-up of pus in the kidney called an abscess.
Remedies For Uti Due To Constipation
The infection should be treated with a suitable antibiotic. You should see your doctor and get an antibiotic.
Drinking plenty of water will produce enough urine flow and help clear the infection.
Reducing the acidity of the urine can help control the infection and reduce the symptoms. There are many over the counter preparations available such as Ural, Citralite, and Citravescent.
Want a home remedy? Then try cranberry juice. Studies show that drinking cranberry juice can help prevent UTI. However, cranberry juice is not enough to treat a full-blown bladder infection.
Relieving your constipation is one of the top priorities in the treatment. Taking an over the counter laxative can be a quick fix for your problem.
To get a long term relief, you should eat fiber-rich foods. Alternatively, you can use a fiber supplement such as Metamucil.
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Drink Plenty Of Liquids
Drinking plenty of liquids, particularly water, will help to wash bacteria from your bladder and urinary tract.
Drinking cranberry juice or taking cranberry extracts may also help prevent urinary tract infections . However, you should avoid cranberry juice or extracts if you’re taking warfarin, a medicine used to prevent blood clots. Cranberry juice can make the effects of warfarin more potent, so there’s a risk of excessive bleeding.
Tips To Avoid Kidney Stones
- Drink plenty of fluid, especially water. This is the most important thing you can do to lower your risk of getting another kidney stone. Aim for at least 2 ½ liters to 3 liters of fluid each day. People with cystine stones may want to aim for 4 liters .
- It may be helpful to limit animal protein, including meat, fish, seafood, poultry, and eggs.
- Eat calcium-rich foods instead of taking supplements.
- If you want to take a vitamin C supplement, make sure you take less than 1000 milligrams per day. High amounts of vitamin C may increase your risk of stones.
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Food Tastes Like Metal
Why this happens:
A build-up of wastes in the blood can make food taste different and cause bad breath. You may also notice that you stop liking to eat meat, or that you are losing weight because you just dont feel like eating.
What patients said:
Foul taste in your mouth. Almost like youre drinking iron.
I dont have the appetite I had before I started dialysis, I must have lost about 10 pounds.
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What Causes A Kidney Infection
Most kidney infections develop from a bladder infection . Bacteria travel up the tube between the bladder and kidney to infect a kidney. These bacteria are usually those normally living in the bowel – eg, E. coli. Most people with cystitis don’t get a kidney infection.
Some kidney infections develop without a bladder infection. This is sometimes due to a problem in the kidney. For example, people are more prone to kidney infections if they have a kidney stone or an abnormality of the kidney.
It is usually only one kidney that develops an infection. A kidney infection can occur at any age. It is much more common in women. This is because women are more at risk of developing a bladder infection . In women, the urethra is closer to the anus, which makes it easier for bacteria to get from the bowel to the urethra. The urethra is also shorter in women than in men, so bacteria can reach the bladder more easily.
Kidney infections are also more common in children, in older people and during pregnancy. They are uncommon in men.
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When To See A Gp
See a GP if you feel feverish and have pain that will not go away in your tummy, lower back or genitals.
Contact a GP immediately if you think your child may have a kidney infection.
If you cannot get a GP appointment and need urgent medical attention, go to your nearest urgent care centre .
If you do not have a local UCC, go to your nearest A& E.