What Should I Ask My Doctor
The sections above describe the typical dosages provided by the drug manufacturer. If your doctor recommends Cialis for you, theyll prescribe the dosage thats right for you.
Remember, you should not change your dosage of Cialis without your doctors recommendation. Only take Cialis exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.
Here are some examples of questions you may want to ask your doctor:
- How long should I give Cialis a chance to work before talking with my doctor about adjusting my dosage?
- Is once-daily or occasional dosing of Cialis more effective for erectile dysfunction?
- How can I tell if my Cialis dosage might need to be lowered?
- Would a different dosage raise or lower my risk for side effects from this drug?
For information about nutrition, sex, stress relief, and more, sign up for Healthlines mens health newsletter.
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Cialis Side Effects Center
Cialis is a phosphodiesterase inhibitor used for treating impotence . Common side effects of Cialis include: flushing , headaches, stomach upset, diarrhea, flu-like symptoms , memory problems, muscle or back pain, nausea, low blood pressure, dizziness, blurred vision and changes in color vision, abnormal ejaculation, and prolonged erections . Tell your doctor if you have rare but serious side effects of Cialis including: a painful or prolonged erection lasting 4 or more hours sudden decreased vision a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. The recommended dose of Cialis is 5-20 mg per day taken before sexual activity. Cialis may interact with rifamycins, antibiotics, antifungals, antidepressants, barbiturates, drugs to treat high blood pressure or a prostate disorder, heart or blood pressure medications, HIV or AIDS medications or seizure medications. Tell your doctor all medications and supplements you use. Cialis is not approved for use in women and has not been evaluated in women who are breastfeeding. Our Cialis Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.Continue reading > >
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How Should I Take Cialis
Cialis is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Cialis can be taken with or without food.
Do not break or split a tablet. Swallow it whole.
For erectile dysfunction, take Cialis just before sexual activity but not more than once per day.
Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor’s instructions.
Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.
Store at room temperature away from moisture and heat.
Cialis And Heart Medications
Cialis is safe for men with healthy hearts, but anyone with cardiovascular disease should take special precautions, and some men cannot use Cialis under any circumstances. This is because Cialis can amplify the effects of some medications for heart conditions.
Organic nitrates are widely used to treat heart conditions predominantly Angina to help lower blood pressure and widen blood vessels. They do this by increasing the supply of nitric oxide to arteries.
Nitric oxide activates guanylate cyclase, which helps convert guanosine triphosphate into cyclic guanosine monophosphate , which supports vasodilation. However, PDE5 inhibitors interact with nitrates to create more cGMP. So if you mix heart medication consisting of nitrates with Cialis, your arteries will get a far stronger hit of cGMP, and you risk a significant drop in blood pressure.
Even healthy men given a mix of a PDE5 inhibitor with a nitrate medication saw their blood pressure drop by 2551 mm Hg, a potentially dangerous amount. The possible effects of this are dizziness, fainting, heart attack, or a stroke.
Cialis stays active in your body for about two days after youve taken it, but longer if you have problems with your kidney or liver. Sometimes additional medications can make you metabolise Cialis more slowly, too. Its therefore very important that you avoid taking nitrates and Cialis within 2448 hours of each other.
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Sildenafil Citrate For Prophylaxis Of Nephropathy In An Animal Model Of Contrast
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Affiliation Department of Pharmacology, University of Michigan, Ann Arbor, MI, United States
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Affiliation Department of Pharmacology, University of Michigan, Ann Arbor, MI, United States
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Affiliation Unit for Laboratory Animal Medicine, University of Michigan, Ann Arbor, MI, United States
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Affiliation Department of Pharmacology, University of Michigan, Ann Arbor, MI, United States
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Affiliation Department of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, United States
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How Can I Get The Maximum Effect From Cialis
To get the maximum effect from Cialis, take it exactly as prescribed.
If youre using once-daily Cialis for either erectile dysfunction or benign prostatic hyperplasia , take your dose around the same time each day. This helps keep a consistent amount of the drug in your body to provide the maximum effect. If you forget to take doses, skip doses, or take doses late, the medication wont work as well.
If youre prescribed occasional Cialis for ED, its best to take your dose at least 2 hours before having sex. This is because it takes an average of 2 hours for the drug to reach its highest level in your body.
Because this is an average, you may notice better effects if you have sex a little sooner or a little later than this 2-hour timeframe. In studies, Cialis improved erectile function as soon as 30 minutes to as long as 36 hours after a dose was taken. As long as you do not take more than the maximum daily dose, you can experiment with how long you wait to have sex after taking a dose.
If you have other questions about how to get the most from Cialis, talk with your doctor or pharmacist.
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Cialis For Erectile Dysfunction
Cialis is FDA-approved to treat erectile dysfunction.
ED is a condition in which a man may have trouble having or maintaining an erection so they can have sex. There are many different causes of ED, including:
- illness
- emotional factors, such as stress, depression, or anxiety
Sometimes ED can be helped by simply addressing the cause, such as treating an illness or anxiety. In other cases, you may need medication such as Cialis to treat your ED.
Effectiveness
Cialis was shown in clinical trials to be an effective medication to treat ED. The drug was studied using part of a survey called the International Index of Erectile Function . A higher score on the IIEF meant that erectile function was better, so ED symptoms improved. The people in the study took the survey after 4 weeks.
One trial looked at people who took 20 mg of Cialis or a placebo only when needed to treat their ED.
- People who took Cialis had their IIEF scores improve by 6.9 to 9.3 points. This means that their ED symptoms eased while they were taking Cialis.
- People who took a placebo either lost points or improved by a maximum of only 0.3 points. Losing points on the scale means that their ED symptoms worsened.
In another trial, people took 2.5 mg or 5 mg of Cialis, or a placebo on an everyday basis to treat their ED.
Dosage For Benign Prostatic Hyperplasia
For symptoms of benign prostatic hyperplasia, the recommended dosage of Cialis is 5 mg once a day. You should take the drug at about the same time each day.
In some cases, your doctor may have you take 5 mg of Cialis a day along with finasteride to treat BPH. If you take both Cialis and finasteride, youll usually take these two drugs for up to 26 weeks.
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Thedrugs And Supplements That Should Cause Concern
The following drugs andsupplements can affect kidney function:
1. NSAIDS
NSAIDs are very effectivemedications for multiple medical problems. But taking NSAIDS can affectthe kidneys, and can cause damage, especially if youre also takingdiuretics or ACE inhibitors.
NSAIDS include over-the-counterpainkillers like aspirin , ibuprofen , and naproxen .
They also includeprescription drugs like:
- Naproxen sodium .
- Naproxen/esomeprazole .
- Diclofenac .
Using these medications withcaffeine can further harm your kidneys. When taking these medications, be sureto check regularly with your doctor if you have impaired kidney function.
2. Antibiotics
Certain antibiotics areremoved from the body through the kidneys, so taking them can put extra strainon your kidneys. Penicillin, cephalosporins and sulfonamides in particular canbe harmful to your kidneys.
Long-term antibiotic use caninjure your kidneys, even if youre otherwise healthy. And for people whosekidneys arent functioning at 100% to begin with, antibiotics can build up inthe body and cause damage.
Despite this, its importantto keep in mind that antibiotics can be safely used if needed as long as thedose is adjusted for your bodys level of kidney function.
3. Dietary supplements
Certain herbs or nutritionalsupplements are associated with kidney injury, even among healthy people. Withsuch a wide variety of supplements available, the best way to know if asupplement is safe is to ask your doctor to review all the ingredients.
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Who Should Not Take This Medication
Do not take tadalafil if you:
- are allergic to tadalafil or any ingredients of this medication
- have had vision loss caused by an eye condition called nonarteritic anterior ischemic optic neuropathy
- are taking the medication riociguat or other similar medications
- are taking any type of nitrate medication in any form . Nitrate medications include nitroglycerin and related medicines that are used for the relief of chest pain or angina. They also include amyl nitrite “poppers.” Use of these medications with tadalafil could cause a sudden severe drop in blood pressure that could lead to dizziness, fainting, heart attack, or stroke.
Nitrates are found in medications that are used to treat angina . If you are not sure if you are taking nitrates, ask your doctor or pharmacist. Nitrates must NOT be taken by anyone who is using tadalafil because they can cause your blood pressure to drop very low. This may cause dizziness, fainting, heart attack, or stroke.
Do I Need A Prescription For Viagra
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Superoxide Dismutase Activity Measurement
SOD activity in rat kidney tissue and serum was measured using spectrophotometry . Blood was removed by washing the tissue with PBS, and specimens were then placed in homogenization buffer . The homogenates obtained were centrifuged at 1550g for 5 min . These were used for SOD measurement following 1:250 dilution. Results were read at a 450nm wavelength. Rat serum specimens were studied using the same method with 1:50 dilution.
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Can A Person With Kidney Problems Take Cialis Or Viagra
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Cialis And Birth Control
Cialis isnt approved for use in women. And its not known if the drug is safe to take during pregnancy.
If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Cialis.
For more information about taking Cialis during pregnancy, see the Cialis and pregnancy section above.
Recommended Reading: Does Seltzer Water Cause Kidney Stones
Does Cialis Increase Testosterone Levels
Testosterone levels can go up and down, but there is a lot you can do to keep them in the normal range. Nowadays, there are a lot of products that promise to boost hormone levels, but many of them fail. The answer to the question does Cialis increase testosterone levels is complex and requires more research, but current evidence shows it can.
A study from the journal Andrologia found that subjects who took tadalafil experienced improved testosterone levels compared to baseline values. Scientists concluded that 5mg tadalafil a day could be beneficial for men with ED and low testosterone, especially when metabolic syndrome accompanies the low-T problem .