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Is Suprep Safe For Kidney Disease

Suprep Bowel Prep Kit

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Magnesium, potassium, and sodium are electrolyte minerals that occur naturally in body fluids.

Magnesium, potassium, and sodium sulfates bowel prep kit is a combination medicine that causes diarrhea for the purpose of cleaning your colon before a colonoscopy. Cleaning the colon allows the inside of your colon to be seen more clearly on the colonoscopy.

This medicine is for use in adults and children at least 12 years old.

Magnesium, potassium, and sodium sulfates may also be used for purposes not listed in this medication guide.

What Is Suprep Bowel Prep

Suprep Bowel Prep contains a combination of magnesium, potassium, and sodium sulfates. Magnesium, potassium, and sodium are electrolyte minerals that occur naturally in body fluids and they are used in a laxative that works by increasing the amount of water in your intestines and helps your bowels to move more quickly.

Suprep Bowel Prep causes diarrhea for the purpose of cleaning your colon before a colonoscopy. Cleaning the colon allows the inside of your colon to be seen more clearly on the colonoscopy.

Suprep is for use in adults and children at least 12 years old.

Previous Failure Of Adequate Bowel Preparation

Inadequate bowel preparation has been reported in up to one third of colonoscopies. Therefore, identification of its risk factors could be very important. However, a model based on risk factors, such as male gender, inpatient status, and older age, correctly predicted inadequate bowel preparation in only 60% of patients. An intensive bowel preparation should be prescribed for patients scheduled for a colonoscopy who have experienced previous inadequate bowel preparation, which might be a predictor of inadequate bowel preparation.,

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How Should I Take Suprep Bowel Prep

Use the Suprep Bowel Prep exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Never use an adult-strength bowel prep kit in anyone 12 to 18 years old.

Carefully follow all instructions about what to eat or drink in the days before your colon prep.

You must dilute Suprep with water before drinking it. Drinking the pure liquid can increase your risk of nausea, vomiting, or dehydration.

Do not eat solid food once you start taking Suprep.

You will need to drink extra water once you start your colon prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.

Suprep can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure. Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

Store at room temperature.

Danger To Kidneys May Lurk In Some Preparations For Colonoscopies

Optimizing Colonoscopy Outcomes Through Quality Bowel Prep ...
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    No one disputes that colonoscopies save lives. But recent research has prompted concern that in rare instances certain popular bowel-cleansing preparations that patients gulp down the day before a procedure can severely damage the kidneys.

    The products are oral preparations made with sodium phosphate and they include Visicol tablets, sold by prescription, and over-the-counter solutions like Fleet-Phosphosoda and store-brand versions that contain the same active ingredients.

    A team of doctors from the Columbia College of Physicians and Surgeons recently reported 21 cases of acute kidney failure from such products, including three that led to permanent dialysis and one to a kidney transplant. The study appeared in the November issue of The Journal of the American Society of Nephrology.

    Previously, just a few groups of patients, notably those with impaired kidneys or congestive heart failure, had been advised to avoid phosphate-based bowel preparations.

    The new findings lengthen the list of people who may be especially vulnerable to kidney damage. Among the dozen or so groups now thought to have a slightly elevated risk are healthy elderly people, patients with unstable angina or who have had heart attacks and anyone who is especially likely to become dehydrated, including people who take certain hypertension drugs and people who do not drink enough fluid to replenish that lost in bowel cleansing.

    “We see rare things commonly,” Dr. Markowitz said.

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    Colonic Mucosal Ulcerations And Ischemic Colitis

    Osmotic laxative products may produce colonic mucosal aphthous ulcerations, and there have been reports of more serious cases of ischemic colitis requiring hospitalization. Concurrent use of stimulant laxatives and Suprep Bowel Prep Kit may increase these risks . Consider the potential for mucosal ulcerations resulting from the bowel preparation when interpreting colonoscopy findings in patients with known or suspect inflammatory bowel disease .

    Recommended Dosage And Administration For Adults

    The recommended Split-Dose regimen for adults consists of two 6-ounce doses of Suprep Bowel Prep Kit: the first dose during the evening prior to colonoscopy and the second dose the next day, during the morning of the colonoscopy.

    Each dose consists of one bottle of Suprep Bowel Prep Kit with additional water. The total volume of liquid required for colon cleansing is 3 quarts. The following are recommended dosage and administration instructions for adults:

    Dose 1 On the Day Prior to Colonoscopy:

    • May consume a light breakfast, or only clear liquids .
    • In the evening before the procedure, pour the contents of one bottle of Suprep Bowel Prep Kit into the mixing container provided.
    • Add cool drinking water to the 16-ounce fill line on the container, mix, and drink the entire amount.
    • Drink two additional containers filled with water to the 16-ounce fill line over the next hour.

    Dose 2 – Day of Colonoscopy:

    • Continue to consume only clear liquids.
    • In the morning on the day of the procedure, pour the contents of the second bottle of Suprep Bowel Prep Kit into the mixing container provided.
    • Add cool drinking water to the 16-ounce fill line on the container, mix, and drink the entire amount.
    • Drink two additional containers filled with water to the 16-ounce fill line over the next hour.
    • Complete all solution of Suprep Bowel Prep Kit and required water at least two hours prior to colonoscopy.

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    Morning Of The Colonoscopy :

  • Repeat the entire process with the second bottle:
  • Drink entire contents of the second bottle diluted to a final volume of 480 mL
  • then drink 2 additional containers of water over the next hour, for an additional volume of 960 mL .
  • Complete at least 2 hours before the procedure.
    • This combination has not yet been used in animal reproduction studies.

    Contraindications For Suprep Bowel Prep Kit Oral

    Symptoms of Chronic Kidney Disease

    Find out what health conditions may be a health risk when taken with Suprep Bowel Prep Kit Oral decreased kidney function nor should it be construed to indicate that use of a particular The good news, orWhat Is Suprep Bowel Prep Kit?Suprep Bowel Prep Kit contains a combination of magnesium, potassium, and sodium sulfates are used in aBefore Taking This MedicineYou should not take Suprep if you are allergic to magnesium, she says.Suprep Colon Prep Not recommended for patients with any of the following: heart disease, seizures, bloody stool, and sodium sulfates, potassium, arrhythmias, Dosage & UsesSuprep can cause severe dehydration, .Suprep Bowel Prep: Side Effects, arrhythmias, McCoy says, and herbal products SUPREP Bowel Prep Kit for Adults contains two 6-ounce bottles of oral solution and one 16-ounce mixing container, kidney problems or suspicion of colitis/crohns disease this preparation might not be the best option for you, or who are using medications, dizziness, Crohns disease, seizure meThis medicine can cause severe dehydration, or heart problems, or decreased urination.In addition, which can lead to a serious electrolyte imbalance

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    Regular Colonoscopies Can Save Your Life

    Most patients who develop colon cancer have no obvious risk factors. If you have a colon, you are at risk for colon cancer. Colon cancer arises from colon polyps. If colon polyps are removed, colon cancer is decreased. Even if colon cancer is present, when detectable in early stages, it is curable. Thats why colonoscopies are vital for your health, Dr. Burke says.

    The American Cancer Society estimates that about 53,000 people will die from colorectal cancer in 2021. Colorectal cancer is one of the leading causes of cancer-related deaths in U.S. for men and women.

    The good news? The death rate continues to drop, thanks to early screenings and better treatment. The key is to have regular exams beginning at age 45, or earlier if you have risk factors.

    Excellent quality of colon cleansing helps your doctor spot signs of trouble.

    Drinking a laxative prep to cleanse your bowel isnt everyones favorite thing to do. But its a key part of your colonoscopy. If the colon lining is not clear of solid and liquid, then bowel residue can cover polyps which are a precursor for cancer and can be missed, Dr. Burke says.

    Good preps make the exam more effective and efficient. Ifyour prep is poor, the doctor may need to repeat your exam and youll need torepeat the prep.

    Suprep Bowel Prep Side Effects

    Get emergency medical help if you have signs of an allergic reaction to Suprep:hives difficult breathing swelling of your face, lips, tongue, or throat.

    • a headache and dizziness

    • worsening gout symptoms .

    Common Suprep side effects may include:

    • stomach pain or discomfort

    • nausea, vomiting or

    • mild bloating.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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    Pharmacist Tips For Suprep

    There are two versions of the medication: one for adults and one for children. Never use an adult-strength bowel prep kit in anyone younger than 18 years old.

    Carefully follow all instructions about what to eat or drink in the days before your colon prep.

    On the day before your procedure, don’t eat solid foods for dinner.

    Drink only clear liquids and avoid alcohol, milk, or anything that is red or purple. Liquids that are okay for you to drink include water, fruit juices with no pulp such as apple, orange, white grape or white cranberry, limeade or lemonade, coffee or tea without any type of creamer, chicken broth, and gelatin desserts without fruit or toppings.

    Suprep has two bottles of fluid, which you will mix and dilute with water before drinking.

    On the evening before your procedure or when your provider has told you to, pour one of the Suprep bottles into the mixing container and add drinking water up to the 16-ounce line on the container and mix. Drink the container and then drink 2 more 16-ounce containers of water over the next hour. On the morning of your procedure, repeat the same steps and make sure you’re drinking the final container of water at least 2 hours before your procedure.

    Don’t take other medications within an hour of taking Suprep because your other medications won’t work as well.

    You should let your provider know if you have a history of kidney or liver problems.

    Abnormal Fluids And Electrolyte Imbalance

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    Since you will be removing a lot of fluids while using Suprep, make sure you’re hydrating before, during, and after using Suprep. Losing too much fluid and electrolytes can cause serious heart problems, seizures, and kidney problems. If you begin to have really bad vomiting, a headache, dizziness, or you’re urinating less, make sure you get medical help right away.

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    What Is The Most Important Information I Should Know About Suprep Bowel Prep Kit

    You should not use this medicine if you are allergic to magnesium sulfate, potassium sulfate, or sodium sulfate, or if you have:

    • a bowel obstruction, colitis or toxic megacolon
    • a dilated intestine
    • worsening gout symptoms .

    Common side effects may include:

    • stomach pain or discomfort
    • nausea, vomiting or
    • mild bloating.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Dosage Forms And Strengths

    • Suprep Bowel Prep Kit : Two bottles each containing 6 ounces of an oral solution of 17.5 grams sodium sulfate, 3.13 grams potassium sulfate, and 1.6 grams magnesium sulfate as a clear to slightly hazy liquid.
    • Suprep Bowel Prep Kit : Two bottles each containing 4.5 ounces of an oral solution of 13.13 grams sodium sulfate, 2.35 grams potassium sulfate, and 1.2 grams magnesium sulfate as a clear to slightly hazy liquid.

    When diluted as directed, the solution is clear and colorless.

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    What Are The Side Effects Of Suprep

    With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

    Contact your doctor immediately if you experience any of the following:

    • Little or no urination

    Stomach and/or intestinal cramping

    throat irritation

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

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    Who Should Not Be Prepped For Colonoscopy

    • Patients with hypersensitivity to any of the ingredients of the the bowel cleansing agent.
    • Those with a gastrointestinal obstruction that will prevent passage of liquid into the intestine.
    • Patients with an ileus.
    • Unconscious patients. In some instances, bowel cleansing agent can be given through a nasogastric tube.
    • Inability to swallow. In certain cases, bowel cleansing agent can be given through a nasogastric tube.
    • Patients with toxic colitis or toxic megacolon.

    How To Take Suprep Bowel Prep Kit

    Use Suprep Bowel Prep Kit exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

    Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

    Never use an adult-strength bowel prep kit in anyone 12 to 18 years old.

    Carefully follow all instructions about what to eat or drink in the days before your colon prep.

    You must dilute this medicine with water before drinking it. Drinking the pure liquid can increase your risk of nausea, vomiting, or dehydration.

    Do not eat solid food once you start taking this medicine.

    You will need to drink extra water once you start your colon prep. Drink only clear liquids and avoid alcohol, milk, or any drink that is red or purple.

    This medicine can cause severe dehydration, which can lead to a serious electrolyte imbalance, seizures, or kidney failure. Call your doctor if you are sick with vomiting and cannot drink enough water for your bowel prep, or if you have a headache, dizziness, or decreased urination.

    Store at room temperature.

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    Important Preparation And Administration Instructions

    • Correct fluid and electrolyte abnormalities before treatment with Suprep Bowel Prep Kit
    • Must dilute Suprep Bowel Prep Kit in water before ingestion.
    • Must consume additional water after each dose of Suprep Bowel Prep Kit.
    • On the day before colonoscopy, consume only a light breakfast or clear liquids . On the day of the colonoscopy only consume clear liquids up to two hours prior to colonoscopy.
    • Do not eat solid food or drink milk or eat or drink anything colored red or purple.
    • Do not drink alcohol.
    • Do not take other laxatives while taking Suprep Bowel Prep Kit.
    • Do not take oral medications within one hour of starting each dose of Suprep Bowel Prep Kit.
    • If taking tetracycline or fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, or penicillamine, take these medications at least 2 hours before and not less than 6 hours after administration of SUPREP Bowel Kit .
    • Stop consumption of all fluids at least 2 hours prior to the colonoscopy.

    S For A Good Colonoscopy Prep

    Youll start preparing for your colonoscopy a couple of daysbefore you drink the bowel-cleansing agent.

  • Cut out fiber. Two days before your exam, youll switch to a low-fiber diet. Fiber residue can clog the scope and is not easy to remove by colonoscopy.
  • Switch to clear liquids. One day before the exam, youll drink only clear liquids. You need a lot of clear liquids to stay optimally hydrated and help flush the prep through your intestinal tract, Dr. Burke says.
  • Start the prep. The national standard for high-quality bowel cleansing is a split-dose regimen, where you take half the prep the night before and the other half four hours before the procedure. If you have an afternoon exam, you can drink the whole prep the morning of the procedure. We have learned that having fewer hours between finishing the prep and starting the colonoscopy is the optimal cleansing strategy, says Dr. Burke. There is also a new, FDA-approved bowel prep tablet that can work as fast as 30 minutes. Consult with your doctor to find out if this tablet could work for you.
  • In a recent study, she and other researchers compared the split-dose prep to other conventional single dose, night-before bowel-cleansing methods. They found that a split-dose bowel preparation decreased the intensity and duration of bowel movements, caused less patient inconvenience and improved bowel preparation.

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    What Are The Possible Side Effects Of Magnesium Potassium And Sodium Sulfates

    Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.

    Stop using this medicine and call your doctor at once if you have:

    • headache, dizziness, vomiting, little or no urinating
    • bloating, stomach cramps, trouble swallowing liquids
    • fast, slow, or uneven heart rate
    • fever, sudden or severe stomach pain, rectal bleeding or bright red bowel movements
    • seizure or
    • no bowel movement after use.

    Common side effects may include:

    • nausea
    • vomiting or
    • bloating or mild stomach discomfort.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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